cell permeability — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2721	Digitonin		Others
	Digitonin is a natural product of the glycoside family and is a detergent. Digitonin has antitumor activity, binds to cholesterol molecules to increase the permeability of cell membranes, and is active in the cleavage of...		Others
T10760	Ceramides Mixture		Telomerase
	Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ...		Telomerase
T8490	Butoconazole	1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole	Antifungal
	Butoconazole (1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole) is an imidazole antifungal agent		Antifungal
T2670	ML167	NCGC00188654,CID44968231	DYRK , CDK
	ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.		DYRK , CDK
T2456	Tivozanib	AV-951,KRN951	VEGFR , PDGFR , Ephrin Receptor
	Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.		VEGFR , PDGFR , Ephrin Receptor
TF0083	POPE
	POPE is a compound found in Escherichia coli, part of the cell membrane, and can be used to study changes in cell membrane permeability.
TN1990	Norathyriol		Akt , DNA/RNA Synthesis , AMPK , PPAR
	Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.		Akt , DNA/RNA Synthesis , AMPK , PPAR
T18988L	FITC-Dextran (MW 4000)	FITC-Dextran (60842-46-8 MW 4000)	Others
	FITC-Dextran (MW 4000) is a marker composed of fluorescein isothiocyanate conjugated to 4 kDa dextran, widely used in microcirculation and cell permeability studies.		Others
T7486	Imeglimin hydrochloride	EMD 387008 hydrochloride	Reactive Oxygen Species , Mitochondrial Metabolism
	Imeglimin hydrochloride (EMD 387008 hydrochloride) prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.		Reactive Oxygen Species , Mitochondrial Metabolism
T0146	Tioconazole	UK-20349,Vagistat	Antibiotic , Antifection , Antifungal
	Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and pr...		Antibiotic , Antifection , Antifungal
T15458	H2DCFDA	2',7'-Dichlorodihydrofluorescein diacetate,DCFH-DA	Reactive Oxygen Species
	H2DCFDA (DCFH-DA) belongs to the class of green fluorescent dyes and is a probe for the detection of intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) with cell membrane permeability.		Reactive Oxygen Species
T2213	Terconazole	Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470	Antifection , Antifungal
	Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damag...		Antifection , Antifungal
T1497	Liranaftate	Piritetrate,M-732	Antifungal
	Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ...		Antifungal
T6802	CFSE	5(6)-CFDA N-succinmidyl ester,Carboxyfluorescein succinimidyl ester,CFDA-SE,5(6)-Carboxyfluorescein diacetate succinimidyl ester	Others
	CFSE (CFDA-SE) is a fluorescent dye with cell membrane permeability. CFSE irreversibly binds to intracellular proteins in living cells and is used for the detection of cell proliferation. The labeled cells fluoresce in g...		Others
T9646	Stafib-2		STAT
	Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM, respectively.Stafib-2 has poor cell permeability.		STAT
T8851	I3MT-3	HMPSNE	Hippo pathway
	I3MT-3 (HMPSNE) (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST...		Hippo pathway
T8641	Vancomycin		Antibacterial , Antibiotic , Autophagy
	Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibiting ribonucleic acid synthesis. Vancomycin can be used for the treatmen...		Antibacterial , Antibiotic , Autophagy
T1438	Butoconazole nitrate	RS 35887	Estrogen/progestogen Receptor , Antifungal
	Butoconazole Nitrate is the nitrate salt form of butoconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate (RS 35887) interferes with steroid biosynthesis by inhibiting the conversi...		Estrogen/progestogen Receptor , Antifungal
T6961	PX-478	PX-478 2HCl	HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
	PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability. PX-478 has antitumor activity and also protects pancreatic β-cell function in diabetes mellitus and is used in type 2 di...		HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
T6686	Sulconazole mononitrate	Exelderm,Sulconazole Nitrate,RS 44872	Antibacterial , Antibiotic , Antifungal
	Sulconazole mononitrate (Exelderm) is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole mononitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demeth...		Antibacterial , Antibiotic , Antifungal